Based on the technology of traditional Amplification Refractory Mutation System (AMRS),PAP-ARMS innovatively combines pyrophosphorolysis-activated polymerization reaction (PAP) to form PAP-ARMS®patent technology,which overcomes the long-standing problems of the traditional ARMS technology,including the poor specificity that may cause some false positive results and difficulties in improving sensitivity and so forth.
Technical Flowchart of PAP-ARMS® Technology
PAP-ARMS® Technical Vantages
1.Have very strong specificity, can perform the detection of mutation with single- digit copy number, and increase the sensitivity to 0.1%.
2. Easy and fast to operate, can be used in the ordinary fluorescence quantitative PCR platform.